Your Current Location is:Home > Application

BASF's Replacing phosgene process

Author:    Release time:2014-04-24 17:06:26      Reading times:

BASF is pursuing ionic liquids in many different directions: another that is under development is ‘‘nucleophilic HCl’’.

巴斯夫公司(BASF)开发的基于<a href=http://ionike.com/e/tags/?tagname=%E7%A6%BB%E5%AD%90%E6%B6%B2%E4%BD%93&tempid=29 target=_blank class=infotextkey>离子液体</a>的1,4-丁二醇氯化工艺--1.jpg

QUILL showed that hydrogen chloride can act as a chlorinating agent towards arenes, generating chloroarenes. In a parallel development, BASF demonstrated that hydrogen chloride in ionic liquids can act as a phosgene substitute. The reaction of butan-1,4-diol with phosgene85 generates 1,4-dichlorobutane in essentially quantitative yield:

If the reaction is attempted with hydrogen chloride instead of phosgene, four products are formed, and the desired 1,4-dichlorobutane is only a minor by-product, the major products being tetrahydrofuran and 1-chlorobutan-4-ol: However, if the hydrogen chloride is dissolved in an ionic liquid, then almost pure 1,4-dichlorobutane is obtained (98% selectivity).

1.  Natalia V. Plechkova and Kenneth R. Seddon. Chem. Soc. Rev., 2008, 37, 123–150.
2.  BASF. Chlorination with ‘nucleophilic HCl’ [EB/OL]. http://www.intermediates.basf.com/chemicals/ionic-liquids.
3.  Stegmann V,Massonne K. Method for producing haloalkanes from alcohols:WO,2005026089[P]. 2005-03-24.
  • Research Institute

  • Application Area

  • Ionic Liquids Used

Previous Article:BASIL TM (Biphasic Acid Scavenging utilising Ionic Liquids) process
Next Article:IFP's Difasol process based on ionic liquids